Here's a link to the news article: http://www.reuters.com/article/idUSTRE6045JT20100105
The article starts,"An acid found in pomegranates appears to block aromatase, an enzyme that converts androgen to estrogen, a hormone that plays a role in the development of breast cancer, the researchers wrote in the journal Cancer Prevention Research." It gives us a few clues.
Good: There are a few familiar items: acid, pomegranate, hormone, estrogen, breast cancer. Some might even be familiar with enzyme. A beginning step in Reach Reading(TM) is to identify any words we don't know and define them. Granted this takes time, but, ultimately, it speeds up comprehension. It is important to use articles on topics of interest to the student when doing reach reading. I would have students bring in the initial science articles that they find in the newspaper or on line. Ah, there is another clue, "Journal of Cancer Prevention Research."
Jot down a few ideas about what you know already:
- breast cancer
http://www.medterms.com/script/main/art.asp?articlekey=15844 Check it out:
The definition goes on and talks about breast cancer. You might want to come back to it later if it wasn't yet helpful, so, keep good track of where you got your information. Remember, we found this at:
http://www.medterms.com/script/main/art.asp?articlekey=15844. Accessed 14 Jan 2010.
French: "L’aromatase est une enzyme du groupe Cytochrome P450 qui permet de convertir les androgènes surrénaliens comme la testostérone en œstrogène ..." fr.wikipedia.org/wiki/Aromatase
German: "Die Aromatase (CYP19A1) ist ein Enzym der Cytochrom-P450-Superfamilie. Seine Funktion ist die Aromatisierung von Testosteron zu Estradiol und von .." de.wikipedia.org/wiki/Aromatase, or, "ein Enzym im menschlichen Organismus, durch dessen Wirkung Vorstufen des weiblichen Geschlechtshormons Östrogen in das aktive Hormon umgewandelt ..." www.mamazone.de/obere-navigation/glossar/, or, "Ein Enzym, welches nach den Wechseljahren Androgene in Östrogene umwandelt. Aromatasehemmer blockieren das Enzym..." www.ueberleben-mit-brustkrebs.de/brustkrebs/service/glossar/content-121465.html
Portuguese: A aromatase pertence ao grupo das enzimas do citocromo p450 e age como mediador da aromatização de andrógenos em estrógenos. pt.wikipedia.org/wiki/Aromatase
Perhaps reading definitions in other languages will help you, though, often the science words are cognates and are very similar to eachother in many languages.
Now, you try finding definitions for other words you don't know, for example, if you don't know, "androgen," you can look that up.
We can scan the article and see if a scientist is mentioned. Yes, there, in the next paragraph, "Shiuan Chen." Looking further, I found this information via Google: "Requests for reprints: Shiuan Chen, Department of Surgical Research, Beckman Research Institute of the City of Hope, 1500 East Duarte Road, Duarte, CA 91010. Phone: 626-256-4673, ext. 63454; Fax: 626-301-8972; E-mail: firstname.lastname@example.org." The Chen article is on white button mushrooms, however: http://cancerres.aacrjournals.org/cgi/content/full/66/24/12026 (Anti-Aromatase Activity of Phytochemicals in White Button Mushrooms (Agaricus bisporus)
(Notice first, however, that the article gives contact information for the authors: "1 Department of Surgical Research, Beckman Research Institute of the City of Hope, Duarte, California and 2 Department of Human Nutrition, The Ohio State University, Columbus, Ohio.")
But at the January 2010 issue of Cancer Prevention Research, http://cancerprevention research.aacrjournals.org/current.dtl, we find, " Lynn S. Adams, Yanjun Zhang, Navindra P. Seeram, David Heber, and Shiuan Chen. Cancer Prev Res 2010 3: 108-113. doi: 10.1158/1940-6207.CAPR-08-0225[Abstract] [Full Text] [PDF] ." There is the original source for the abundance of articles found in the news today about pomegranate. The article itself will give you a mouthful, for example, "On consumption, pomegranate ETs hydrolyze, releasing ellagic acid, which is then converted to 3,8-dihydroxy-6H-dibenzo[b,d]pyran-6-one ("urolithin") derivatives by gut microflora, " where every other word (or nearly so) is an unknown...(so, we can go back to the definition game...) If you have breast cancer, or, know someone that does, you'll likely want to understand every word (Or, if not, you might want to bring a copy of the article to you doctor's office, so he or she will know, you've, "Done your homework.")
I hope that this has made, "Reach Reading (TM)" fun for you. If not, we'll try again another day. My students love it, but, perhaps not being with me in the classroom, but, rather. on-line, it might not come across as as much fun. Please give me feedback and ask me questions.
P.S.: Either men or woman can get breast cancer, so, I hope that you found the article of interest. Now that you are one of the world's few that knows about , "aromatase." perhaps you'd like to Reach Read(TM) what it has to do with the prostate: http://cat.inist.fr/?aModele=afficheN&cpsidt=17598374.
(c) 2010 J S Shipman